By Harry G. Brittain

ISBN-10: 0122608305

ISBN-13: 9780122608308

While following within the footsteps of earlier volumes via offering finished studies of drug ingredients and extra fabrics, this name additionally heralds an important enlargement of the scope of the sequence. conventional contributions will now even be augmented by way of booklet of severe assessment chapters that summarize details relating to the characterization of drug ingredients and excipients. this modification is needed to raised meet the wishes of the pharmaceutical communtiy and to permit the advance of a well timed motor vehicle for publishing assessment fabrics in this topic.The scope of the Profiles sequence will surround overview articles and database compilations that fall inside of one of many following six vast different types: actual profiles of drug components and excipients; Analytical profiles of drug elements and excipients; Drug metabolism and pharmacokinetic profiles of drug components and excipients; Methodologoy on the topic of the characterization of drug components and excipients; tools of chemical synthesis; and reports of the makes use of and purposes for person drug elements, periods of drug ingredients, or excipients. - offers entire reports overlaying all facets of drug improvement and formula of substances - Now encompassing severe evaluation chapters - Meets the data wishes of the drug improvement neighborhood

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Additional resources for Analytical Profiles of Drug Substances, Excipients, and Related Methodology

Example text

2 Formulae. . . . . . . . . . . . . . . 1 Empirical formula, molecular weight, CAS number . . . . . . . . . . . . . 2 Structural formula . . . . . . . . . 3 Elemental analysis . . . . . . . . . . . . 4 Appearance . . . . . . . . . . . . . . 5 Uses and applications . . . . . . . . . . . 1 History . . . . . . . . . . . . . 2 Therapeutic aspects . . . . . . . . . Method of Preparation. . . . . . .

1 Systematic chemical name. . . . . . . 2 Nonproprietary name. . . . . . . . 3 Proprietary names . . . . . . . . . 2 Formulae. . . . . . . . . . . . . . . 1 Empirical formula, molecular weight, CAS number . . . . . . . . . . . . . 2 Structural formula . . . . . . . . . 3 Elemental analysis . . . . . . . . . . . . 4 Appearance . . . . . . . . . . . . . . 5 Uses and applications . . . . . . .

23 . . . . . . . . . . . . . . . . 24 23 23 23 23 24 24 24 24 24 24 25 26 27 27 27 28 28 30 31 31 31 34 35 35 35 35 35 35 36 42 42 42 42 42 44 46 5. 6. 7. 8. 9. 10. CEFTRIAXONE SODIUM: COMPREHENSIVE PROFILE 23 Stability . . . . . . . . . . . . . . . . . . . Pharmaceutical Dosage Forms . . . . . . . . . . . Drug Metabolism and Pharmacokinetics . . . . . . . 1 Pharmacokinetics . . . . . . . . . . . . . 1 Absorption and plasma concentrations .

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Analytical Profiles of Drug Substances, Excipients, and Related Methodology by Harry G. Brittain


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